VISDB Viral Integration Site DataBase

VIS ID

TVIS44017374

Fusion event

HTLV-1-MARK2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.1

Reference genome

Start

End

63672337/63904865 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-99a-5p ; hsa-mir-93-5p ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-6780b-5p ; hsa-mir-3150a-3p ; hsa-mir-6763-5p ; hsa-mir-190a-5p ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-92a-1-5p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4489 ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6823-5p ; hsa-mir-6132 ; hsa-mir-296-3p ; hsa-mir-6805-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-6774-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3202 ; hsa-mir-4722-5p ; hsa-mir-7515 ; hsa-mir-4459 ; hsa-mir-7843-5p ; hsa-mir-4761-3p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-17-3p ; hsa-mir-181a-3p ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-455-3p ; hsa-mir-639 ; hsa-mir-7151-5p

Nearest miRNA

hsa-mir-129-2/Upstream/1112094; hsa-let-7a-2/Downstream/436984;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/64863, chr11-CpG: 40/Downstream/3982

Upstream sequence

CCCCACTTCTCTTCCCACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTA

Downstream sequence

ACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTC