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TVIS44017377
Basic Information
VIS ID
TVIS44017377
Fusion event
HTLV-1-ATG2A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64662906/64895434 (Hg38)
End
64662906/64895434 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA11H
Target gene
ATG2A
miRNAs that regulate target gene
hsa-mir-3175
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-1273g-3p
;
hsa-mir-6849-3p
;
hsa-mir-7703
;
hsa-mir-106b-5p
;
hsa-mir-20a-5p
;
hsa-mir-3692-3p
;
hsa-mir-5095
;
hsa-mir-7151-3p
;
hsa-mir-4653-3p
;
hsa-mir-6798-5p
;
hsa-mir-4717-3p
;
hsa-mir-6805-5p
;
hsa-mir-6514-5p
;
hsa-mir-4802-3p
;
hsa-mir-4697-5p
;
hsa-mir-4488
;
hsa-mir-1237-5p
;
hsa-mir-6816-5p
;
hsa-mir-3196
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-198
;
hsa-mir-6808-3p
;
hsa-mir-7150
;
hsa-mir-7973
;
hsa-mir-885-3p
;
hsa-mir-139-3p
;
hsa-mir-3688-3p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-4758-3p
;
hsa-mir-4286
;
hsa-mir-488-5p
;
hsa-mir-4323
;
hsa-mir-550b-2-5p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-4276
;
hsa-mir-1227-3p
;
hsa-mir-4504
;
hsa-mir-766-3p
;
hsa-mir-5190
;
hsa-mir-508-5p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-1193
;
hsa-mir-1233-3p
;
hsa-mir-1276
;
hsa-mir-3064-5p
;
hsa-mir-370-5p
;
hsa-mir-376a-3p
;
hsa-mir-376b-3p
;
hsa-mir-4687-3p
;
hsa-mir-4760-3p
;
hsa-mir-6501-3p
;
hsa-mir-6504-5p
;
hsa-mir-6801-5p
;
hsa-mir-7974
;
hsa-mir-892b
;
hsa-mir-146b-3p
;
hsa-mir-1914-5p
;
hsa-mir-6779-3p
Nearest miRNA
hsa-mir-10392/Upstream/3995; hsa-let-7a-2/Downstream/2929;
Nearest TSS
ENST00000527297/Upstream/1985;
ENST00000413292/Downstream/2296;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/26
,
chr11-CpG: 31/Downstream/21693
Upstream sequence
GGCAGGCTGCTGGCCCCTGCGCAGCCTCCGCGCAGAGCGCTTATCCTGCAGGGAGCGGGAGACGGGGGCTGCCGGGGACAGGATGTCATACACGGTCTCA
Downstream sequence
GCTGTGGCCTGGGGGACATGGGAGCACTGGATGAGGACAGCTGGCTGGGGCACACGTCAGCCCCAGGCCCCCAGGACAGTCTGAGACCCCACCAGCCCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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