Basic Information
VIS ID
TVIS44017381
Fusion event
HTLV-1-LOC102724064 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
66127127/66359656 (Hg38)
End
66127127/66359656 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
LOC102724064
Nearest miRNA
hsa-mir-10392/Upstream/710403; hsa-let-7a-2/Downstream/574778;
Nearest TSS
ENST00000527297/Upstream/11441; ENST00000639555/Downstream/11991;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/11602, chr11-CpG: 95/Downstream/11679
Nearby gene
SLC29A2(-2865) ;
Upstream sequence
GGTGACCTCAGTCAACAGTAGTTTGTTCAAGAAACCTTGAGAAGAAAGAAAGAGAGCAAGAAGAACAAGGATGCCACCTGGCTCCATCTAGGATATCATG
Downstream sequence
ATGACTCTAGTGACCACAAAGCAATTCCCCATTCTATTATGTTGTTGACCCTGCCTGTGACCTTGACCCTGCCTATGACCTATTCCTTCTAATGTGCCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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