VISDB Viral Integration Site DataBase

VIS ID

TVIS44017386

Fusion event

HTLV-1-CPT1A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.3

Reference genome

Start

End

68575187/68807719 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRA11H ; FRA11A

Target gene

miRNAs that regulate target gene

hsa-mir-370-3p ; hsa-mir-155-5p ; hsa-mir-16-5p ; hsa-mir-197-3p ; hsa-mir-5581-3p ; hsa-mir-6716-5p ; hsa-mir-1298-5p ; hsa-mir-194-3p ; hsa-mir-1324 ; hsa-mir-6789-3p ; hsa-mir-4707-3p ; hsa-mir-4258 ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-129-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4438 ; hsa-mir-5089-5p ; hsa-mir-6878-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-7162-3p ; hsa-mir-4786-5p ; hsa-mir-544b ; hsa-mir-6849-3p ; hsa-mir-4459 ; hsa-mir-4433a-3p ; hsa-mir-4768-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-1272 ; hsa-mir-1322 ; hsa-mir-4293 ; hsa-mir-4517 ; hsa-mir-4322 ; hsa-mir-4296 ; hsa-mir-4265 ; hsa-mir-6514-3p ; hsa-mir-4666b ; hsa-mir-7977 ; hsa-mir-4417 ; hsa-mir-6781-5p ; hsa-mir-6877-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-6869-3p ; hsa-mir-299-3p ; hsa-mir-33a-5p

Nearest miRNA

hsa-mir-10392/Upstream/762762; hsa-let-7a-2/Downstream/275457;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/24594, chr11-CpG: 49/Downstream/31577

Upstream sequence

CTGGCTGGACATGCAGTTGCTGTGGAGACAGACCCAGACAAGGGAGGCTGTGCGTGAGGCCACACGGTGCCACCAACACCACCGGTGACGCCACAGACAC

Downstream sequence

CACGTGCTGCAGGGTCCAGCAGCCTGCCCCAGGTACAGCCGGGAAAGTCAGAGGGAGAGCACTTGCAGGAACTGAGCTCTTAAAACACTCACGGGCACTC