Basic Information
VIS ID
TVIS44017387
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
68894068/69126600 (Hg38)
End
68894068/69126600 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA11H ; FRA11A
Nearest miRNA
hsa-mir-10392/Upstream/43342; hsa-let-7a-2/Downstream/1157355;
Nearest TSS
ENST00000527297/Upstream/23107; ENST00000641280/Downstream/28878;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/43517, chr11-CpG: 30/Downstream/30622
Nearby gene
LOC338694(No orient, 20628)
Upstream sequence
GGAATGGCCTTTGTGTCTCACCTGCCGCAGGGGTCTGACTCTGACCTTCCTCAGGGACCCTACCATTCCAGGGTTCTGTACCCCATGCGGCGACTGTCCA
Downstream sequence
GCCTTGCTTGAGGCCCACCTCTCCCCATATGCTGATGACACCGTCGtcctgacaatagcctgagaggcaggtcctgtgtgggttgtactctgtggatggg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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