Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene905541986933518910951882921488364108837231884200788654088869398882554288292108869755887308588634018865081887400188744008874385
Basic Information
VIS ID
TVIS44017414
Fusion event
HTLV-1-ST5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
8895932/8874385 (Hg38)
End
8895932/8874385 (Hg38)
Orient
+
Location type
Intronic
Target gene
ST5
miRNAs that regulate target gene
hsa-mir-98-5p
Nearest miRNA
hsa-mir-210/Upstream/1639548; hsa-let-7a-2/Downstream/215927;
Nearest TSS
ENST00000527297/Upstream/2967; ENST00000524577/Downstream/35526;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/3148, chr11-CpG: 64/Downstream/36641
Nearest cancer related gene
ST5(TSG, No orient, 0)
Upstream sequence
CATACAGATGCCTGGCAACACATCTTGTAGCTAAGGGTCTGTTTAATATTTTAACCTTGAGAGCCTTATAATTCAACTACTTTGTTATATACCAAAATAG
Downstream sequence
AACTTGACATCACAAAGATGAGCTTTACTTCCTTTTGCTATTTTAAATCCTGCACTTAAGCATGGTGAGTTGTCTGGGTTTTCTGGTTCATGGATTTTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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