Basic Information
VIS ID
TVIS44017429
Fusion event
HTLV-1-RPS6P19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
101622510/101228732 (Hg38)
End
101622510/101228732 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPS6P19
Nearest miRNA
hsa-let-7i/Upstream/1038783; hsa-mir-1178/Downstream/2701693;
Nearest TSS
ENST00000382841/Upstream/18325; ENST00000551998/Downstream/51377;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/18577, chr12-CpG: 30/Downstream/51280
Nearby gene
SLC5A8(-18494) ;
Upstream sequence
GGTCTATAACAGGAATGCCCCTACTCAGTAGCAGTAGGCAGACCCAGCCATGGGTCAGGACACACTGCTTCATGAGGAAACCTTGTTCGTTGGTCCCACC
Downstream sequence
ACTGACTCGGACCACATAACTCTTCCAGAGCGTCGGCAGCAACCTCTGTGCCATATGCTTCTCATAAGTACAAAATTGCCATTCGTTGTCCAATCCAATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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