Basic Information
VIS ID
TVIS44017431
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
102657762/102263984 (Hg38)
End
102657762/102263984 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/2074035; hsa-mir-1178/Downstream/1666441;
Nearest TSS
ENST00000382841/Upstream/66139; ENST00000635615/Downstream/40371;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/143813, chr12-CpG: 38/Downstream/560358
Nearby gene
PMCH(-66139) ;
Upstream sequence
GAGAAATTCTTCATGCATGTTAAATTTTTTTTAAAGATTACTAAAACCTTTAATAAAATTGTAATAGCTTTTACTTTTGAAAGATAAAATTTCAACTTAA
Downstream sequence
TCTTGTAGCTCAGAAGTTTATTCTATGATAGTGACATTTGATTTTGGCTGGATGTTGATTCTAATACTTTGCCCTTTGTCATACAGCTAAAGTACATATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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