Basic Information
VIS ID
TVIS44017434
Fusion event
HTLV-1-C12orf42 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
103904117/103510339 (Hg38)
End
103904117/103510339 (Hg38)
Orient
-
Location type
Intronic
Target gene
C12orf42
Nearest miRNA
hsa-let-7i/Upstream/3320390; hsa-mir-1178/Downstream/420086;
Nearest TSS
ENST00000382841/Upstream/14329; ENST00000551174/Downstream/37455;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/14274, chr12-CpG: 87/Downstream/330156
Nearby gene
C12orf42(No orient, 14329)
Upstream sequence
gtgaagtaactcaggaatagaaaaccaaacatcaaacattctcactcatagttgggagctaagctatgataggatacaaaggcataagaatgatacaatg
Downstream sequence
gactttggggatttgggggtaagtgtgggaaggagtgagggataaaagactacaaattgggttcagtgtatactgcttgggtgatgggcacaccaaaatc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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