Basic Information
VIS ID
TVIS44017457
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
123222226/122737679 (Hg38)
End
123222226/122737679 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/28255; hsa-mir-3612/Downstream/272988;
Nearest TSS
ENST00000382841/Upstream/6836; ENST00000537955/Downstream/15095;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/210461, chr12-CpG: 68/Downstream/14768
Nearby gene
HCAR1(-7097) ;
Upstream sequence
aaacaaacaaacaaaaaaacacagaaaataagcattggcaaaattgtggagaaactgaaacccttgtgcattgttggtgggaatgcaaaatatggaaaac
Downstream sequence
aatgcggcagttactaaaaatattgagatccagcaattctacttctggatatatgcctgaaagaattgaaagcagggacttgaacaggtatttgtacact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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