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TVIS44017497
Basic Information
VIS ID
TVIS44017497
Fusion event
HTLV-1-SENP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
48444070/48050287 (Hg38)
End
48444070/48050287 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
SENP1
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-375
;
hsa-mir-133a-3p
;
hsa-mir-183-5p
;
hsa-mir-34a-5p
;
hsa-mir-192-5p
;
hsa-mir-18a-3p
;
hsa-mir-138-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-1277-5p
;
hsa-mir-297
;
hsa-mir-3924
;
hsa-mir-190a-3p
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-let-7f-2-3p
;
hsa-mir-4789-5p
;
hsa-mir-98-3p
;
hsa-let-7f-1-3p
;
hsa-let-7b-3p
;
hsa-let-7a-3p
;
hsa-mir-223-5p
;
hsa-mir-567
;
hsa-mir-511-3p
;
hsa-mir-5011-5p
;
hsa-mir-5580-3p
;
hsa-mir-590-3p
;
hsa-mir-3191-5p
;
hsa-mir-5571-5p
;
hsa-mir-6885-3p
;
hsa-mir-5579-3p
;
hsa-mir-4694-5p
;
hsa-mir-7162-5p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-5009-3p
;
hsa-mir-3124-3p
;
hsa-mir-4264
;
hsa-mir-4797-3p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-4768-3p
;
hsa-mir-1264
;
hsa-mir-519d-3p
;
hsa-mir-93-5p
;
hsa-mir-20b-5p
;
hsa-mir-17-5p
;
hsa-mir-145-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/686018; hsa-let-7i/Downstream/82510;
Nearest TSS
ENST00000382841/Upstream/9526;
ENST00000546755/Downstream/15393;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/44698
,
chr12-CpG: 65/Downstream/55393
Upstream sequence
TGACTAAGAAAACAGGCACATTTTTCAGAATGCTTTTTGGGGAATGGGAAAATGCCCCTGTTCTTTGACAAATATTTACACACCAGGATGCCAGAACAGT
Downstream sequence
GAGCTACTGCCCAACAGTAAGCAACGACATACTGGGTAGGCAGCAGGGGAACACTGCCAGGAACACACCGGAGCACGGTCTAGACCAGAGAAAGGGCCTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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