Basic Information
VIS ID
TVIS44017505
Fusion event
HTLV-1-CALCOCO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
54115777/53721993 (Hg38)
End
54115777/53721993 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
CALCOCO1
Nearest miRNA
hsa-mir-1244-3/Upstream/664981; hsa-let-7i/Downstream/269745;
Nearest TSS
ENST00000382841/Upstream/2215; ENST00000566418/Downstream/3274;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/26364, chr12-CpG: 18/Downstream/16371
Upstream sequence
AACCTATTTCCTTGATGCCAGAACCATTGTAAAAGCCCACTAACATCTCTCCTTCACCCTCTTCACTGGGTTCAGATTTTGGATGCTGGGTGAGCAGCCA
Downstream sequence
GGCCCTGTCCCCTACCTGGCCCAGCTCCCACCTTGTACTGTTCCATCAGCTCCGTGTGCTCCTGCCTGGCAGTTGCCAGAGCCCTCTCGAGCTCCTGCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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