Basic Information
VIS ID
TVIS44017511
Fusion event
HTLV-1-ANO2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
6011454/5902288 (Hg38)
End
6011454/5902288 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANO2
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-3649/Upstream/4241908; hsa-let-7i/Downstream/1061411;
Nearest TSS
ENST00000382841/Upstream/20482; ENST00000538418/Downstream/42971;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/74369, chr12-CpG: 46/Downstream/42895
Upstream sequence
AAAAGCAGACCAATTAGGTTGCTTATTCACTTTTTTAAAAAACTCACGATAACAAGCTATATTAATACACTTAAATTTGGATGTGAGATTTAAGAATGGC
Downstream sequence
ATTCAAAATAGCTAggctggacaagatggttcatgcctttaatcccagcactttgggtggctgaggcaggaggatggcttggagccaggagtttgcaatc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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