Basic Information
VIS ID
TVIS44017518
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
64990950/64597170 (Hg38)
End
64990950/64597170 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/773443; hsa-mir-1178/Downstream/25339;
Nearest TSS
ENST00000382841/Upstream/63532; ENST00000540088/Downstream/12289;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/144636, chr12-CpG: 132/Downstream/12843
Nearby gene
RASSF3(+13343) ;
Nearest cancer related gene
RASSF3(TSG, +13343) ;
Upstream sequence
TGTATTTTTTTTTAACACGTTGGCCTTCACATATCTGGTCAATTTTTCTCCAttttattttattttttaatttttttcctgagatggagccttgctctgt
Downstream sequence
tgcccagactggagtgcagtggctcgatcttcgctcactgcaacctccacctcctgggttcaagcagttctccttcctcagcccctcgagtagctgggat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate