Basic Information
VIS ID
TVIS44017531
Fusion event
HTLV-1-LOC105369844 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
76033190/75639410 (Hg38)
End
76033190/75639410 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369844
Nearest miRNA
hsa-let-7i/Upstream/6054587; hsa-mir-1178/Downstream/3779847;
Nearest TSS
ENST00000382841/Upstream/127774; ENST00000549888/Downstream/52948;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/127672, chr12-CpG: 142/Downstream/391653
Nearby gene
KRR1(-127772) ;
Upstream sequence
AAATGTTTTTTGGGAACAGGAAATTTTCATCCGATTGAACATTTAGGTAAAATAAATTTCTCTCTCCATTCCAGAGGTACATTCTTATTTTTATGAATTG
Downstream sequence
GCTAGTGACTGGAGCTGGTTAAAAAATGGTGCAAACTCTGTGAGTTCACTAGCACTTTGTTAAATGAAATTGATCACTTGTAAAATACAGTAATTGCATT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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