VISDB Viral Integration Site DataBase

VIS ID

TVIS44017532

Fusion event

HTLV-1-NAP1L1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

q21.2

Reference genome

Start

End

76463592/76069812 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-30a-5p ; hsa-mir-877-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-30a-3p ; hsa-mir-26b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-555 ; hsa-mir-545-5p ; hsa-mir-6768-5p ; hsa-mir-1537-5p ; hsa-mir-5692a ; hsa-mir-6509-5p ; hsa-mir-331-5p ; hsa-mir-5591-3p ; hsa-mir-660-5p ; hsa-mir-101-3p ; hsa-mir-196b-5p ; hsa-mir-196a-5p ; hsa-mir-569 ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4802-5p ; hsa-mir-655-5p ; hsa-mir-582-5p ; hsa-mir-6504-3p ; hsa-mir-4803 ; hsa-mir-202-3p ; hsa-let-7i-5p ; hsa-mir-98-5p ; hsa-let-7f-5p ; hsa-mir-4458 ; hsa-let-7g-5p ; hsa-mir-4500 ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7a-5p

Nearest miRNA

hsa-let-7i/Upstream/6484989; hsa-mir-1178/Downstream/3349445;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/37276, chr12-CpG: 132/Downstream/14125

Upstream sequence

ATAAAGTGAAGACTTCTGAGTCTAGCTCTTGTTTAGAACAAAGCCAAGATGATAGCACCATTCAAAGAGAAGGTTAAAAATTAATAAGATAGCATCCTTC

Downstream sequence

CCATTTCATCTTAAAAAAAAAAAATCACCAAAAATCTAATTATTGAACATGAGATTACATCTAGCATTAGAAAGGAAAATAAGGATTCCTAAGTCAATGT