Basic Information
VIS ID
TVIS44017561
Fusion event
HTLV-1-MCF2L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
113612468/112958154 (Hg38)
End
113612468/112958154 (Hg38)
Orient
+
Location type
Intronic
Target gene
MCF2L
Nearest miRNA
hsa-mir-1267/Upstream/2617125; hsa-mir-4502/Downstream/304766;
Nearest TSS
ENST00000623511/Upstream/55959; ENST00000433807/Downstream/7977;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/14181, chr13-CpG: 98/Downstream/10269
Nearby gene
MCF2L-AS1(-9330) ;
Nearest cancer related gene
MCF2L(OG, No orient, 0)
Upstream sequence
CAGCTGTCGCCGTCAGTCTTCCTCAGATGCCAGTTTGTTGAGGTGTTTCTCTTTCCCTGATGCCTCTTGTGCCAACAAATAAAGACTTTCAGCTCTTCCT
Downstream sequence
GGGCTCTCGAGACCAGGCCTGCTGCAttctcagagaagcagaaccttaggagatgcgtggacgtgcgtggttcgtctgtgccccgtgtcatgggctggct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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