Basic Information
VIS ID
TVIS44017562
Fusion event
HTLV-1-MCF2L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
113669464/113015150 (Hg38)
End
113669464/113015150 (Hg38)
Orient
-
Location type
Intronic
Target gene
MCF2L
Nearest miRNA
hsa-mir-1267/Upstream/2674121; hsa-mir-4502/Downstream/247770;
Nearest TSS
ENST00000623511/Upstream/13257; ENST00000486806/Downstream/9514;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2133, chr13-CpG: 21/Downstream/1465
Nearest cancer related gene
MCF2L(OG, No orient, 0)
Upstream sequence
TGGGAGGAGGTGGGTGGAGGAGGGTCAGGGTCCCCAGGGGGATGTGGCCTGGGCACCCCTGACAGCAGCCTCCAGGGACAGATGGAGTGGTGTGTGGGTG
Downstream sequence
GCCGAGCCCATGGGCCTCAGTGAACCCCAGTTCCTGCTGCATCTGGGCACCTCCCAGGCCACGCCTCTGTCCACTGTGGCCTCCAGCCCTGCGTCTGGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate