Basic Information
VIS ID
TVIS44017580
Fusion event
HTLV-1-MTUS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
29617022/29042885 (Hg38)
End
29617022/29042885 (Hg38)
Orient
-
Location type
Intronic
Target gene
MTUS2
miRNAs that regulate target gene
hsa-mir-146a-5p ; hsa-mir-124-3p ; hsa-mir-4761-3p
Nearest miRNA
hsa-mir-2276/Upstream/4880381; hsa-mir-1267/Downstream/10621149;
Nearest TSS
ENST00000623511/Upstream/222537; ENST00000255289/Downstream/29099;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/222124, chr13-CpG: 31/Downstream/296864
Upstream sequence
tgtatttctgtggtagcagttataatatcccctgttttgtttctaatctagtttatttggatcttccctcctcttttcttggctaatcttgctaatggtc
Downstream sequence
tatcaattttgtctatcttttcaaagacctagcttttgtttcatttatcttttgtataattttttcttacaattgtatttagttctgctctgatctttgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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