VISDB Viral Integration Site DataBase

VIS ID

TVIS44017608

Fusion event

HTLV-1-FNDC3A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr13

Cytoband

q14.2

Reference genome

Start

End

49729381/49155245 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-1-3p ; hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-let-7a-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-573 ; hsa-mir-646 ; hsa-mir-3616-5p ; hsa-mir-4635 ; hsa-mir-4670-3p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-142-3p ; hsa-mir-206 ; hsa-mir-561-3p ; hsa-mir-551b-5p ; hsa-mir-613 ; hsa-mir-1303 ; hsa-mir-544a ; hsa-mir-7850-5p ; hsa-mir-6505-5p ; hsa-mir-202-3p ; hsa-mir-323a-3p ; hsa-mir-4668-3p ; hsa-mir-302c-5p ; hsa-mir-513a-5p ; hsa-mir-3143 ; hsa-mir-3160-5p ; hsa-mir-4711-5p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-499b-5p ; hsa-mir-4494 ; hsa-mir-543 ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-129-5p

Nearest miRNA

hsa-mir-2276/Upstream/4959045; hsa-mir-1267/Downstream/841170;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/178339, chr13-CpG: 150/Downstream/65005

Upstream sequence

cctggactctttttggttggtaaactattgattatcgccacaatttcagctcctgttattggtctattcagggattcaccttcttcctggtttagtcttg

Downstream sequence

ggagattgtatgtgtcgaggaatttatccatttcttctagattttctagtttatttgcgtagaggtgtttgtagtattctctgatggtagtttgtatttc