Basic Information
VIS ID
TVIS44017622
Fusion event
HTLV-1-LOC105370223 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
59850318/59276184 (Hg38)
End
59850318/59276184 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B ; FRA13C
Target gene
LOC105370223
Nearest miRNA
hsa-mir-1297/Upstream/4101636; hsa-mir-1267/Downstream/1923614;
Nearest TSS
ENST00000623511/Upstream/1043067; ENST00000435636/Downstream/420009;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1641388, chr13-CpG: 52/Downstream/887342
Nearby gene
DIAPH3(-389403) ;
Upstream sequence
agatgaaaactctaagaattaaaaaaaaatgctagaagtaaaatttgctaagacagaaatgaaaaacgcctttaatgggctcatcagtacagtagatata
Downstream sequence
gccaaggaaagaatcagtgagcttgaagatatgtcaatagaaatgcctcaaactgaaaagcagagatttatttaaaagagaaaaaaaaaaaactggaaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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