Basic Information
VIS ID
TVIS44017674
Fusion event
HTLV-1-IGH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
106879745/106423838 (Hg38)
End
106879745/106423838 (Hg38)
Orient
+
Location type
Intronic
Target gene
IGH
Nearest miRNA
hsa-mir-1185-1/Upstream/564285; hsa-mir-5195/Downstream/427047;
Nearest TSS
ENST00000550708/Upstream/1620; ENST00000620337/Downstream/1816;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/21962, chr14-CpG: 28/Downstream/36501
Nearby gene
LINC00221(+58700) ;
Upstream sequence
GAAAAATATCAGTAATGAACAGGCCAAAAGAAATGAACCATTATGGAAAGAGAGGTAATGAAATGAAACAATAAATTCCATGTTGAGGTGACAGGGAAGT
Downstream sequence
TCCATCTGAAGCTCATTTTCACCTCTGCGGGTACTGAGTGCCCCCTGCCACCCAGCTCCCACCCTGAAGGGAGGTTTCTGTCTGAGCTCTGTGAGTGAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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