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TVIS44017687
Basic Information
VIS ID
TVIS44017687
Fusion event
HTLV-1-PRKD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
30292812/29823606 (Hg38)
End
30292812/29823606 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRKD1
miRNAs that regulate target gene
hsa-let-7b-5p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-6740-3p
;
hsa-mir-6837-3p
;
hsa-mir-942-5p
;
hsa-mir-3925-3p
;
hsa-mir-766-3p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-208a/Upstream/2190328; hsa-mir-1185-1/Downstream/1191040;
Nearest TSS
ENST00000550708/Upstream/157448;
ENST00000553082/Downstream/103906;
Nearest CpG islands
None/Target,
chr14-CpG: 35/Upstream/1037743
,
chr14-CpG: 147/Downstream/103398
Upstream sequence
CCATTGAATTGATAGCTCTAAATGACAGAATCATTGAATGAATACTATATTGCCACTTCTTTTGTGCTACAAATACAAATACAAAACACTCTTTAATGGA
Downstream sequence
GCACTGTCCTCATTATACAACCGACCACTGACATAAAAGGCAAGAAGGTTAAGCCCACTTTTGAAAAGCTCTTAAGTAACAGGTCAGAGGACAGAAACGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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