Basic Information
VIS ID
TVIS44017711
Fusion event
HTLV-1-LOC105378178 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
49437067/48967864 (Hg38)
End
49437067/48967864 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378178
Nearest miRNA
hsa-mir-208a/Upstream/1206760; hsa-mir-1185-1/Downstream/998535;
Nearest TSS
ENST00000550708/Upstream/476097; ENST00000557531/Downstream/109641;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1291478, chr14-CpG: 30/Downstream/618068
Nearby gene
RPS29(-606323) ;
Upstream sequence
TGTTAACATTTTTATGCTATAAACACTTATGCTTATGATTATTACTTATAATAATTATATTGTGGATTTAAGATTGCCATAGGGAATCACTATCAAAAGG
Downstream sequence
AAAATATTATTAAAAATCTTTTTGTAGTGATTTTTATTGTATGATAATGTAATGTAGCgttttgaaaactgagactcctagttttaaaacatgggccacc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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