Basic Information
VIS ID
TVIS44017716
Fusion event
HTLV-1-LINC01599 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
50503200/50036482 (Hg38)
End
50503200/50036482 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01599
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-208a/Upstream/69971; hsa-mir-1185-1/Downstream/263373;
Nearest TSS
ENST00000550708/Upstream/25093; ENST00000426751/Downstream/2606;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/32781, chr14-CpG: 60/Downstream/79770
Upstream sequence
CCTGCGGCAGGACCTTTGCCAGGGCAGCCACTGAGGGAAGGTAGCCAAGACTTGGAGCACCTTCGGGCTGTGAGCCTCATTCATTCCTGGAGGCAAAAGT
Downstream sequence
GCCCAGGGCAGGCCTAGCTCTGGTGTGGGAGTCAGGAAAGAGAGGAGGTGCAGGGCCGAGGGGAGGATAAGGGGATCAAGGAGGTGATGAAGGAGGCTGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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