Basic Information
VIS ID
TVIS44017728
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
62145366/61678648 (Hg38)
End
62145366/61678648 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA14B
Nearest miRNA
hsa-mir-208a/Upstream/1029937; hsa-mir-1185-1/Downstream/2416376;
Nearest TSS
ENST00000550708/Upstream/31228; ENST00000557446/Downstream/16865;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/355899, chr14-CpG: 112/Downstream/16481
Nearby gene
HIF1A-AS1(No orient, 2393)
Upstream sequence
GCATGGTATTCAGGAGTTAGTTGAAATCAAGATCACTCACTAAGAATAAGCTTAGAAATTATTCAGGCAggccgggcatggtggctcacgcctgtaatcc
Downstream sequence
cagcactttgggaggccaaggtgggtgttcacctgagctgaagagctggagaccagcctgggcaatatggtgaaaattcgtctctccaaaaaaaacaaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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