VISDB Viral Integration Site DataBase

VIS ID

TVIS44017732

Fusion event

HTLV-1-PLEKHG3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q23.3

Reference genome

Start

End

65183628/64716910 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-339-5p ; hsa-mir-511-5p ; hsa-mir-6740-3p ; hsa-mir-3613-3p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-500a-5p ; hsa-mir-4668-3p ; hsa-mir-548c-3p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-1265 ; hsa-mir-2392 ; hsa-mir-122-3p ; hsa-mir-1273h-5p ; hsa-mir-1293 ; hsa-mir-149-3p ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-3165 ; hsa-mir-3192-5p ; hsa-mir-3622a-3p ; hsa-mir-3622b-3p ; hsa-mir-363-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-377-5p ; hsa-mir-4459 ; hsa-mir-4483 ; hsa-mir-4728-5p ; hsa-mir-4786-5p ; hsa-mir-490-3p ; hsa-mir-505-3p ; hsa-mir-544b ; hsa-mir-6086 ; hsa-mir-6087 ; hsa-mir-6134 ; hsa-mir-658 ; hsa-mir-6745 ; hsa-mir-6748-5p ; hsa-mir-6756-5p ; hsa-mir-6765-3p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6801-5p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-7162-3p ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-208a/Upstream/621785; hsa-mir-1185-1/Downstream/68716;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/11621, chr14-CpG: 23/Downstream/26215

Upstream sequence

CCTCGGCCGTGTCTCTACACGTGTGCACCCCAGAATTGGGATTGGGTAATACTGCCCCACCGGTCTGAATTCTGGTCCATGTACGCTCCCAGCTGAGGCA

Downstream sequence

GGAAGTGCCCCTCCTCTACCCAGGAACTGGTTGGATGAGTTTCTTAGGCGTCTCTGGTGAGGCCCCTTAGTAGGGGAAGCGGGGAACATGGGGGATGGGG