Basic Information
VIS ID
TVIS44017744
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
77004927/76538584 (Hg38)
End
77004927/76538584 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/2058380; hsa-mir-1185-1/Downstream/727634;
Nearest TSS
ENST00000550708/Upstream/38938; ENST00000554237/Downstream/188128;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/46853, chr14-CpG: 135/Downstream/222642
Nearby gene
ESRRB(+36747) ;
Nearest cancer related gene
ESRRB(TSG, +36747) ;
Upstream sequence
AAGTTTTGACAATCACCTTCAGCTTAAGCTTTCTGGCATAATTCCCGCTCCCCTTGATCATGCAGCAGACGCTCCTTTCTTTACTTACTCCATCTCATTC
Downstream sequence
ATGCCACCAGCTAATCTTTTCTCCCACTGGCTTCTATGATTCCAGAAAGAAATCTGACTCTTTGCTGTGCCTGACTGGATGCCTACTCAGTCATGTTTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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