Basic Information
VIS ID
TVIS44017745
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
78105163/77638820 (Hg38)
End
78105163/77638820 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/372530; hsa-mir-1185-1/Downstream/16309406;
Nearest TSS
ENST00000550708/Upstream/22047; ENST00000554074/Downstream/65632;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/21913, chr14-CpG: 39/Downstream/3007
Nearby gene
SPTLC2(-22053) ;
Upstream sequence
CCAATCCAATATTCACATGGCAAAGCCCTCCCTATCTACATTTCCTGCATCCAAGAAACCAACCAACTCAGGCTGCAGCCAGCTTCTCAAGCCTAATTCT
Downstream sequence
AAAGTCCACAAAAGAGAATATGCTTGACCCAGTTGTGAGTCATGTACACTCTGTCTCAGTTAATGCCATAGGGGCAAATCACACGCCCAAACATAGCTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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