VISDB Viral Integration Site DataBase

VIS ID

TVIS44017760

Fusion event

HTLV-1-EFCAB11 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q32.11

Reference genome

Start

End

90368774/89902430 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-135b-3p ; hsa-mir-5089-5p ; hsa-mir-6806-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-508-3p ; hsa-mir-6823-3p ; hsa-mir-6506-5p ; hsa-mir-2114-3p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-1273d ; hsa-mir-937-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-8077 ; hsa-mir-5702 ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-6504-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-4438 ; hsa-mir-3929 ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-5580-3p ; hsa-mir-500a-3p ; hsa-mir-6804-3p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-1915-3p ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4695-5p ; hsa-mir-4726-3p ; hsa-mir-495-5p ; hsa-mir-6087 ; hsa-mir-640 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-665 ; hsa-mir-6764-5p ; hsa-mir-6840-3p

Nearest miRNA

hsa-mir-1260a/Upstream/12636140; hsa-mir-1185-1/Downstream/4045796;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/10386, chr14-CpG: 25/Downstream/52126

Upstream sequence

ttttcttgcagtgttttatctctatctgaaattaacttgcttactcagttattatctgtcttctcccaaggaaactgtgaactccctgacagcagggacc

Downstream sequence

ttgtttgctgtgttggtggctctattctcagcatccagaatggcccctggtgtacagaaggtgctccaataaCCACTTTCCAGTAGATTAATAAAAATAT