Basic Information
VIS ID
TVIS44017762
Fusion event
HTLV-1-CALM1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.11
Reference genome
End
90864059/90397715 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-let-7f-5p ; hsa-mir-129-5p ; hsa-mir-450b-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-579-3p ; hsa-mir-595 ; hsa-mir-548c-3p ; hsa-mir-648 ; hsa-mir-664a-3p ; hsa-mir-4760-3p ; hsa-mir-664b-3p ; hsa-mir-548aw ; hsa-let-7c-3p ; hsa-mir-340-5p ; hsa-mir-3123 ; hsa-mir-4311 ; hsa-mir-4729 ; hsa-mir-539-5p ; hsa-mir-586 ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-495-5p ; hsa-mir-1305 ; hsa-mir-1250-3p ; hsa-mir-511-3p ; hsa-mir-548a-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548ar-3p ; hsa-mir-548az-3p ; hsa-mir-493-3p ; hsa-mir-142-3p ; hsa-mir-6867-5p ; hsa-mir-382-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-4696 ; hsa-mir-3163 ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-142-5p ; hsa-mir-5590-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-4639-5p ; hsa-mir-502-5p ; hsa-mir-5589-3p ; hsa-mir-1915-5p ; hsa-mir-6841-3p ; hsa-mir-4662a-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-5696 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1324 ; hsa-mir-382-3p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-6882-5p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-5582-3p ; hsa-mir-3148 ; hsa-mir-4668-5p ; hsa-mir-4777-5p ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-520g-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-625-5p ; hsa-mir-6795-5p ; hsa-mir-6873-5p ; hsa-mir-6887-5p
Nearest miRNA
hsa-mir-1260a/Upstream/13131425; hsa-mir-1185-1/Downstream/3550511;
Nearest CpG islands
chr14-CpG: 175/Target, None/Upstream, None/Downstream
Upstream sequence
CGGGCACTAGAcccccccccccggcccgccccTCCCCACCCCGCTTCTCCGCCGGCGCGAAGGTGGCAGGTCGGGCGGGCAGTGGAGAATGAATGGGCTG
Downstream sequence
GAGCTGGCCGGTGGCGCACATTGTTCCGGCCGGGTGTTGAGGGGCGCAGTCAGCGCCCGCCACCTCCCCACTTTGGCCGGCCCTGCTGGGCGCCCTCCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate