Basic Information
VIS ID
TVIS44017764
Fusion event
HTLV-1-ATXN3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
End
92566641/92100297 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-4528 ; hsa-mir-5096 ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-921 ; hsa-mir-3190-3p ; hsa-mir-142-3p ; hsa-mir-6073 ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6134 ; hsa-mir-1247-3p ; hsa-mir-3174 ; hsa-mir-382-5p ; hsa-mir-4537 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-6079 ; hsa-mir-155-3p ; hsa-mir-4540 ; hsa-mir-6723-5p ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-5002-5p ; hsa-mir-6838-3p ; hsa-mir-5694 ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-4753-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-130b-5p ; hsa-mir-1264 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-193b-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4442 ; hsa-mir-3687 ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-6890-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-7162-3p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-1288-5p ; hsa-mir-6765-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-7847-3p ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-33a-3p ; hsa-mir-377-3p ; hsa-mir-3978 ; hsa-mir-409-3p ; hsa-mir-4799-5p ; hsa-mir-548l ; hsa-mir-6768-5p
Nearest miRNA
hsa-mir-1260a/Upstream/14834007; hsa-mir-1185-1/Downstream/1847929;
Upstream sequence
ataattatgtaatgcatccactaaagcttaatatatacatctcctatgatctagcaattccattactaggtacataatgtaaacaacagcaatgcaaaca
Downstream sequence
tacattcatcaaaagacatgtataagaatgttcacaaaagcagtatttttgtgccacaaatagcattactatttgtagtaatacaaaatagcattacaga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate