Basic Information
VIS ID
TVIS44017768
Fusion event
HTLV-1-DICER1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.13
Reference genome
GRCh37/hg19
Start
95642348/95176011 (Hg38)
End
95642348/95176011 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
DICER1-AS1
Nearest miRNA
hsa-mir-1260a/Upstream/38025; hsa-mir-1185-1/Downstream/4933408;
Nearest TSS
ENST00000550708/Upstream/18001; ENST00000439999/Downstream/1472;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/18128, chr14-CpG: 79/Downstream/143404
Upstream sequence
ttgggttggttccaagtctttgctattgtgaatagtgctgcaataaacatacgtgtgcatgtgtctttatagctgtatgatttataatcctttgggtata
Downstream sequence
tacccagtaatgggatggctgggtcaaatggtatttctagttccagatccttgaggaatcgccacactgtcttccacaatggttgaactagtttacagtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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