Basic Information
VIS ID
TVIS44017794
Fusion event
HTLV-1-DPH6-DT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
35943080/35650879 (Hg38)
End
35943080/35650879 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
DPH6-DT
Nearest miRNA
hsa-mir-1233-1/Upstream/278515; hsa-mir-10393/Downstream/275977;
Nearest TSS
ENST00000557528/Upstream/104496; ENST00000560866/Downstream/205598;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/104565, chr15-CpG: 35/Downstream/928379
Upstream sequence
AGATAAGAGTGATCAGATAGGAGAGGAAGTTTAAATCTAGTTGTCTTAAGtagagtgatcatttgtccaagtgtgtgctgaactgtctaatttatggctg
Downstream sequence
ttgtcctacaatattttttgttgttgttgtgataggtcttgctctgtctccaggctggagtgcagtggcgcgatctccactcactgcaatcttcgcctcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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