Basic Information
VIS ID
TVIS44017804
Fusion event
HTLV-1-LOC105370805 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
48337672/48045475 (Hg38)
End
48337672/48045475 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370805
Nearest miRNA
hsa-mir-10393/Upstream/2612346; hsa-mir-11181/Downstream/1123595;
Nearest TSS
ENST00000557528/Upstream/101431; ENST00000482911/Downstream/75497;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/326628, chr15-CpG: 53/Downstream/132335
Nearby gene
SLC24A5(+75497) ;
Upstream sequence
ttgctttgaccaatagaatgcttagaactgatgatctgggacttctgagttcaggtctcaaaggaactgttagcatcagctttttcttccttgaaagtca
Downstream sequence
actgccaagtggtaaagaggctcaggctatgttgggcgtggtggctcatgcctgtaattccagcactttgggagaccaaggcaagtggatcatttgaggc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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