Basic Information
VIS ID
TVIS44017809
Fusion event
HTLV-1-GABPB1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.2
Reference genome
End
50586359/50294162 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-548e-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-4266 ; hsa-mir-3175 ; hsa-mir-765 ; hsa-mir-135a-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-9500 ; hsa-mir-6750-5p ; hsa-mir-6822-5p ; hsa-mir-5584-5p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-548m ; hsa-mir-1273e ; hsa-mir-6807-5p ; hsa-mir-4451 ; hsa-mir-4746-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-1914-5p ; hsa-mir-4663 ; hsa-mir-8077 ; hsa-mir-4252 ; hsa-mir-655-5p ; hsa-mir-6889-3p ; hsa-mir-7162-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-4537 ; hsa-mir-106a-5p ; hsa-mir-6759-3p ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-192-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6776-5p ; hsa-mir-191-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-6742-3p ; hsa-mir-1273g-3p ; hsa-mir-5694 ; hsa-mir-1229-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-4733-3p ; hsa-mir-1226-3p ; hsa-mir-4719 ; hsa-mir-3145-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-433-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1224-3p ; hsa-mir-1231 ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-3190-5p ; hsa-mir-6504-3p ; hsa-mir-654-3p ; hsa-mir-4438 ; hsa-mir-6771-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-34b-3p ; hsa-mir-619-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3973 ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-510-3p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-4634 ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-5690 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-340-5p ; hsa-mir-4494 ; hsa-mir-7-1-3p ; hsa-mir-7-2-3p
Nearest miRNA
hsa-mir-10393/Upstream/1125009; hsa-mir-11181/Downstream/66167;
Upstream sequence
AAAACCTAGATAATCTGCAGCACCTTTGACGACATCTGAGATCTCTTGTTCAATAAGAATTCTGAATTCAGATGCCATACAAATGAAATAAGGGAAGAAA
Downstream sequence
ACTGTCTTTGAAATGTCCTAAAAGATTGAAAATTCTACATAGAAACATTTAAATAATAAAATAGAAACTATGgaccgggagcagtgctcatgcctgtaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate