VISDB Viral Integration Site DataBase

VIS ID

TVIS44017818

Fusion event

HTLV-1-RNF111 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q22.2

Reference genome

Start

End

59331313/59039114 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-21-5p ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6716-5p ; hsa-mir-31-5p ; hsa-mir-4533 ; hsa-mir-3616-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-5002-3p ; hsa-mir-17-3p ; hsa-mir-4712-3p ; hsa-mir-624-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-2392 ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-6873-5p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-6753-5p ; hsa-mir-1911-3p ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-545-5p ; hsa-mir-3662 ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-153-5p ; hsa-mir-19a-3p

Nearest miRNA

hsa-mir-10393/Upstream/3666080; hsa-mir-11181/Downstream/132069;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/50593, chr15-CpG: 49/Downstream/65957

Nearest cancer related gene

RNF111(TSG, No orient, 0)

Upstream sequence

agtgcaatgacacgatctcagctcaccgcaacctctgcctcccgtgttcaagtgattctcctgcctctgcctcccgagtagctgggattacaggcacgtg

Downstream sequence

ccaccatacctggctaattttttatttttagtagagatgaggtttttccatgttggtcatgctggtctcgaactcctaacctcaggtcatctgcccgcct