VISDB Viral Integration Site DataBase

VIS ID

TVIS44017827

Fusion event

HTLV-1-ZNF609 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q22.31

Reference genome

Start

End

64858944/64566745 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-615-3p ; hsa-mir-30d-5p ; hsa-let-7a-5p ; hsa-mir-218-5p ; hsa-mir-196a-5p ; hsa-mir-196b-5p ; hsa-mir-940 ; hsa-mir-3714 ; hsa-mir-4736 ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-4320 ; hsa-mir-6839-5p ; hsa-mir-378j ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378f ; hsa-mir-378h ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-4272 ; hsa-mir-1243 ; hsa-mir-6757-3p ; hsa-mir-624-3p ; hsa-mir-3149 ; hsa-mir-6083 ; hsa-mir-568 ; hsa-mir-190a-3p ; hsa-mir-3163 ; hsa-mir-410-3p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-1178-5p ; hsa-mir-1182 ; hsa-mir-1200 ; hsa-mir-1203 ; hsa-mir-135a-5p ; hsa-mir-135b-5p ; hsa-mir-1914-3p ; hsa-mir-3165 ; hsa-mir-3184-5p ; hsa-mir-323a-5p ; hsa-mir-3653-5p ; hsa-mir-3689d ; hsa-mir-3915 ; hsa-mir-3928-3p ; hsa-mir-423-5p ; hsa-mir-4299 ; hsa-mir-4324 ; hsa-mir-4456 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4662a-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-5194 ; hsa-mir-544b ; hsa-mir-548q ; hsa-mir-580-5p ; hsa-mir-604 ; hsa-mir-6077 ; hsa-mir-647 ; hsa-mir-6723-5p ; hsa-mir-6734-5p ; hsa-mir-6736-3p ; hsa-mir-6738-5p ; hsa-mir-6762-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p ; hsa-mir-7854-3p ; hsa-mir-7855-5p ; hsa-mir-7978 ; hsa-mir-8069 ; hsa-mir-8071 ; hsa-mir-876-3p ; hsa-mir-889-5p ; hsa-mir-98-5p

Nearest miRNA

hsa-mir-10393/Upstream/695726; hsa-mir-11181/Downstream/195642;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/105667, chr15-CpG: 42/Downstream/136258

Upstream sequence

GTAAAGGAAACAGATATAGAAGAGATAGGGAAAGGTTTAGAGTTGGAGTGTCTTCAGCTGCTTGTGGAGGGCGTGGTAGAGACAGTGTTAACTACTTCCC

Downstream sequence

AGTTTTACCTTGGGTGACCCTTGTTACAGATCACTGCTTCTGAGCTGCTTTTGAGAGCTAGTGGAGAGAGATTATATTACGTCCTAGGAGAATGTAACTC