VISDB Viral Integration Site DataBase

VIS ID

TVIS44017844

Fusion event

HTLV-1-ACSBG1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q25.1

Reference genome

Start

End

78471498/78179156 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1273e ; hsa-mir-7855-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4257 ; hsa-mir-4459 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-374b-3p ; hsa-mir-4766-3p ; hsa-mir-1290 ; hsa-mir-144-5p ; hsa-mir-3908 ; hsa-mir-4703-5p ; hsa-mir-3942-5p ; hsa-mir-4446-5p ; hsa-mir-7152-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-6867-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-623 ; hsa-mir-6740-3p ; hsa-mir-4469 ; hsa-mir-3667-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-513b-5p ; hsa-mir-4450 ; hsa-mir-125b-2-3p ; hsa-mir-4457

Nearest miRNA

hsa-mir-10393/Upstream/2416841; hsa-mir-11181/Downstream/1030632;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/29237, chr15-CpG: 103/Downstream/84907

Upstream sequence

TGGAGCACTGTGATAGGCTGGCAGGGAGAGGAGATATTTAATCATAATAGATGATCCTGCAAATCACTCCCCAGAACTGACCGCCCTCACCGTCCATTAG

Downstream sequence

GAGGCTGGCCTGGTCCCCCCAACTCCTACCCCAGCTGGCCCCTGGGCCATCTGCTCTCCTAGAACACACTGGAGCACACCCCACTCCAAAAGAGGGAGGG