Basic Information
VIS ID
TVIS44017861
Fusion event
HTLV-1-LOC105371078 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10342854/10248997 (Hg38)
End
10342854/10248997 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105371078
Nearest miRNA
hsa-mir-1225/Upstream/4616431; hsa-mir-11401/Downstream/1057443;
Nearest TSS
ENST00000527434/Upstream/66243; ENST00000570163/Downstream/77437;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/65430, chr16-CpG: 22/Downstream/3182
Nearby gene
GRIN2A(-66243) ;
Upstream sequence
gcaactctcctgcctcagcctcccaagtacctgggattacaggcgcacaccaccacacccagctaatttttgtatttttagtagagatggggtttcacca
Downstream sequence
tgtaggccaggctggtctcgagctcctgacctcaggtgaccctcccacctcagactcccaaagtgctgggattacaggcctgagccaccgcacctggcTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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