Basic Information
VIS ID
TVIS44017869
Fusion event
HTLV-1-UMOD integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
20366882/20355560 (Hg38)
End
20366882/20355560 (Hg38)
Orient
-
Location type
Intronic
Target gene
UMOD
Nearest miRNA
hsa-mir-1225/Upstream/1860984; hsa-mir-11401/Downstream/1150489;
Nearest TSS
ENST00000527434/Upstream/2682; ENST00000577173/Downstream/741;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/6384, chr16-CpG: 65/Downstream/385764
Nearby gene
UMOD(-2682) ;
Upstream sequence
tggctcagtcttggctcactgcaacctccacctcccaagttcaagtgattctcttgaatccttgaatcctcagcctcccgagtagctgggattacaggtg
Downstream sequence
cataccaccatgcccggctaatttgtgttttttttgtacacattggccaggctggtctcgaactcctgacctcaggtaatctgcctgcctcggcctccca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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