Basic Information
VIS ID
TVIS44017870
Fusion event
HTLV-1-PDZD9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
22005711/21994390 (Hg38)
End
22005711/21994390 (Hg38)
Orient
+
Location type
Intronic
Target gene
PDZD9
Nearest miRNA
hsa-mir-1225/Upstream/488255; hsa-mir-11401/Downstream/2208726;
Nearest TSS
ENST00000527434/Upstream/14128; ENST00000562695/Downstream/6708;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/159384, chr16-CpG: 115/Downstream/13276
Upstream sequence
ttaagtggctttgcccagggtcacagaactaaaaagtgtcagaccctgagcctgaatcAGGACAGCTAACACAATGTTTTTTCTTTCTCACCATGGCGCC
Downstream sequence
AGCCCATTCTGCCTCCCCAACTCCTGGGCACAGTACTAGGCCCAGGCCAGGCACTGAGAAAACACCTCTTGAACTGCATGGAAAATTCATTCACCCAAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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