Basic Information
VIS ID
TVIS44017876
Fusion event
HTLV-1-HS3ST4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25855944/25844623 (Hg38)
End
25855944/25844623 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
HS3ST4
Nearest miRNA
hsa-mir-1225/Upstream/1641392; hsa-mir-11401/Downstream/180614;
Nearest TSS
ENST00000527434/Upstream/152597; ENST00000475436/Downstream/42123;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/151313, chr16-CpG: 34/Downstream/1265067
Upstream sequence
acagagtctggtagtgatcatttgtgaacatgaatctttgagcacacacacacaataggaacgcttttacactattggtagaaatgttaattagttcaac
Downstream sequence
cattgtggaagacggtgtggcgattcctcaaagatctagaaccagaaataccatttgacccagcaatcccattactgggtatacatccaaaggaatataa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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