Basic Information
VIS ID
TVIS44017884
Fusion event
HTLV-1-SMG1P2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
29603701/29592380 (Hg38)
End
29603701/29592380 (Hg38)
Orient
+
Location type
Intronic
Target gene
SMG1P2
Nearest miRNA
hsa-mir-1225/Upstream/633719; hsa-mir-11401/Downstream/6799;
Nearest TSS
ENST00000527434/Upstream/86381; ENST00000436527/Downstream/70599;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/108403, chr16-CpG: 103/Downstream/2263
Nearby gene
MIR3680-1(No orient, 6799)
Upstream sequence
AAAGCCTAAATCggctgagtgcggtgacttacacctgtaatcccagcactttgggaggccaaagcaggcggatcacctgagtcaggagtccaagaacagg
Downstream sequence
ccggccaacatggtggaatcccgtctctactaaaaatacaaaaattagctggacgcctgtaatcccagctactcaggaggctgaggcaggagaatttttc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate