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TVIS44017891
Basic Information
VIS ID
TVIS44017891
Fusion event
HTLV-1-STX4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31049652/31038331 (Hg38)
End
31049652/31038331 (Hg38)
Orient
+
Location type
Intronic
Target gene
STX4
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-22-3p
;
hsa-mir-5684
;
hsa-mir-5688
;
hsa-mir-618
;
hsa-mir-495-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-6514-3p
;
hsa-mir-7977
;
hsa-mir-128-2-5p
;
hsa-mir-128-1-5p
;
hsa-mir-3178
;
hsa-mir-6781-5p
;
hsa-mir-4284
;
hsa-mir-24-3p
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-4787-5p
;
hsa-mir-6499-5p
;
hsa-mir-5787
;
hsa-mir-4505
;
hsa-mir-4252
;
hsa-mir-5186
;
hsa-mir-3130-3p
;
hsa-mir-1273g-3p
;
hsa-mir-5089-5p
;
hsa-mir-675-5p
;
hsa-mir-4466
;
hsa-mir-2861
;
hsa-mir-4731-5p
;
hsa-mir-5589-5p
;
hsa-mir-661
;
hsa-mir-3116
;
hsa-mir-6778-3p
;
hsa-mir-1254
;
hsa-mir-6506-5p
;
hsa-mir-548q
;
hsa-mir-619-5p
;
hsa-mir-150-5p
;
hsa-mir-939-3p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-17-3p
;
hsa-mir-1827
;
hsa-mir-3929
;
hsa-mir-4419b
;
hsa-mir-4478
;
hsa-mir-455-3p
;
hsa-mir-4722-5p
;
hsa-mir-4763-5p
;
hsa-mir-485-5p
;
hsa-mir-5588-3p
;
hsa-mir-5690
;
hsa-mir-665
;
hsa-mir-6746-5p
;
hsa-mir-6771-5p
;
hsa-mir-6808-5p
;
hsa-mir-6884-5p
;
hsa-mir-6893-5p
;
hsa-mir-6894-3p
;
hsa-mir-940
Nearest miRNA
hsa-mir-1225/Upstream/144346; hsa-mir-11401/Downstream/3125247;
Nearest TSS
ENST00000527434/Upstream/4526;
ENST00000486660/Downstream/179;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/4157
,
chr16-CpG: 29/Downstream/3858
Upstream sequence
CCCCTCTGAGTCCTGTCCGTTTctcgacctcctgggctcaggtgatcctcctgcctcagcctcccgagtagctgggactataggtgcaagccactgcacc
Downstream sequence
ccgctTGCTGTGGCCCTTTCTGATTAAGGGCACCCTGAGGCCTCTAAGGGAATTAATTAGCCTGCCTGGAGTCACCCATCAGATTCCAGGCTGAGGGCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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