Basic Information
VIS ID
TVIS44017902
Fusion event
HTLV-1-MIR5095 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
48526856/48492945 (Hg38)
End
48526856/48492945 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MIR5095
Nearest miRNA
hsa-mir-1225/Upstream/14329272; hsa-mir-11401/Downstream/1799671;
Nearest TSS
ENST00000527434/Upstream/44543; ENST00000563994/Downstream/53639;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/106955, chr16-CpG: 28/Downstream/3679
Upstream sequence
AGTCATCGACAATGCTCTGTGGAGCTCTGGGAAGCCTATCGTAAAGTTATTTAAACTACCACCGAATTCTAGAAGGAATTGCAATGTGGAGTTGCAGTCA
Downstream sequence
GGGTAGACGTTCATGTCCCAGAGGTCACAGCATGTTCCTGTTGCAGCCGCACCCAGATGTTCACAATGGTGGAGACCTTGCTTCCCAGTAACACCAAGTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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