VISDB Viral Integration Site DataBase

VIS ID

TVIS44017934

Fusion event

HTLV-1-TERF2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

69403177/69369274 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-766-3p ; hsa-mir-15b-5p ; hsa-mir-96-5p ; hsa-mir-92a-3p ; hsa-mir-218-5p ; hsa-mir-5692a ; hsa-mir-106a-3p ; hsa-mir-572 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-593-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-767-5p ; hsa-mir-183-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-5197-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3653-5p ; hsa-mir-1248 ; hsa-mir-5088-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-129-5p ; hsa-mir-665 ; hsa-mir-1228-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-4683 ; hsa-mir-7160-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7162-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6888-5p ; hsa-mir-23a-3p ; hsa-mir-1225-3p ; hsa-mir-1233-3p ; hsa-mir-1247-3p ; hsa-mir-139-3p ; hsa-mir-1827 ; hsa-mir-3940-3p ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-6746-5p ; hsa-mir-6808-5p ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-1273g-3p ; hsa-mir-3120-5p ; hsa-mir-3664-5p ; hsa-mir-4252 ; hsa-mir-4522 ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-542-3p ; hsa-mir-6510-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-6888-3p ; hsa-mir-7703

Nearest miRNA

hsa-mir-1225/Upstream/1135775; hsa-mir-11401/Downstream/196534;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/29295, chr16-CpG: 74/Downstream/16351

Upstream sequence

AGGCCAGGCTCAACTATCTTGACACCTGCTGCCTGAATATCCCAAACTACCTGCTTATAAATAATCTGAGATTTGCCAAACGACTGCTAAGATCATGGAC

Downstream sequence

ACTATCCTAATATGGGCCTGGCAGATCTGTTACGAGACAGAATATTTTCCACATTCTCAAAGTCCTGGTTtcttttgcccaggctgaagtgcagtggcac