Basic Information
VIS ID
TVIS44017942
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
74435478/74401580 (Hg38)
End
74435478/74401580 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/4371158; hsa-mir-11401/Downstream/2467356;
Nearest TSS
ENST00000527434/Upstream/20271; ENST00000566506/Downstream/11219;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/32839, chr16-CpG: 76/Downstream/5173
Nearby gene
CLEC18B(-7051) ;
Upstream sequence
gaggattaaatgagAAGAGGAggttgggcaccatggctcacacctgtaatcccagcgctttgggaggccgaggtgggtggatcacctgaggtcaggaatt
Downstream sequence
caagaccagcctggccaatatgatgaaagccagtctctactaaaaataACTTCTTTGCCCAGTTACCTTCTTTTTTTGGGGGATGGGGGTGGGgagacag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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