Basic Information
VIS ID
TVIS44017965
Fusion event
HTLV-1-BANP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
87997835/87964229 (Hg38)
End
87997835/87964229 (Hg38)
Orient
+
Location type
Intronic
Target gene
BANP
miRNAs that regulate target gene
hsa-mir-320a ; hsa-mir-4283 ; hsa-mir-25-5p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4285 ; hsa-mir-6813-5p ; hsa-mir-6085 ; hsa-mir-1286 ; hsa-mir-5681a ; hsa-mir-371a-5p ; hsa-mir-3619-5p ; hsa-mir-761 ; hsa-mir-214-3p ; hsa-mir-6165 ; hsa-mir-888-5p
Nearest miRNA
hsa-mir-11401/Upstream/110265; hsa-mir-4722/Downstream/504689;
Nearest TSS
ENST00000527434/Upstream/850; ENST00000474563/Downstream/2474;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/6239, chr16-CpG: 24/Downstream/20796
Nearest cancer related gene
BANP(OG, No orient, 0)
Upstream sequence
ACATGGGCACAACACACTTTGAAAACCTTAATCCATGGTTTTTAAATAGCATTTCTGACATTCATCATTGTGCATTGGGGAATGACGTCAGTGGTGTGTT
Downstream sequence
CTCACTGGactcatcacagacgtattcactggatgcggtgcgggccaggcccggtgccctgctgagaacacagccatgccaattcctgcccttgtgaagc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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