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TVIS44017989
Basic Information
VIS ID
TVIS44017989
Fusion event
HTLV-1-MAP2K3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21195295/21291983 (Hg38)
End
21195295/21291983 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAP2K3
miRNAs that regulate target gene
hsa-mir-214-3p
;
hsa-mir-20a-5p
;
hsa-mir-124-3p
;
hsa-mir-30a-5p
;
hsa-mir-21-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-218-5p
;
hsa-mir-1227-5p
;
hsa-mir-128-1-5p
;
hsa-mir-128-2-5p
;
hsa-mir-1296-3p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-16-5p
;
hsa-mir-195-5p
;
hsa-mir-28-5p
;
hsa-mir-2861
;
hsa-mir-3139
;
hsa-mir-3151-5p
;
hsa-mir-3619-5p
;
hsa-mir-424-5p
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-4456
;
hsa-mir-4481
;
hsa-mir-4512
;
hsa-mir-4743-5p
;
hsa-mir-4745-5p
;
hsa-mir-497-5p
;
hsa-mir-541-3p
;
hsa-mir-5571-3p
;
hsa-mir-6081
;
hsa-mir-6510-5p
;
hsa-mir-654-5p
;
hsa-mir-6731-5p
;
hsa-mir-6742-5p
;
hsa-mir-6754-5p
;
hsa-mir-6760-5p
;
hsa-mir-6762-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6781-5p
;
hsa-mir-6838-5p
;
hsa-mir-6845-5p
;
hsa-mir-6877-5p
;
hsa-mir-708-5p
;
hsa-mir-761
;
hsa-mir-8085
;
hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-1180/Upstream/1947409; hsa-mir-10226/Downstream/6001927;
Nearest TSS
ENST00000595228/Upstream/514;
ENST00000527123/Downstream/19704;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/6852
,
chr17-CpG: 47/Downstream/24696
Upstream sequence
CTTTCCCAGAGGTCATGGCCCCTTCACCCGTTCATAGGACGTCAAAGGAGGAAACCGAGGCTTGCACAGAGAGGGAGTGTGGCTCGCCCCCAGGCTGGCA
Downstream sequence
CGGGCCGACGCTGTGGTGGTTTCTCCACTGAGGTGCGGGGAAGGCAGGAGCTGGGACCCAGGCTGGGGGCCTGACTCTGCTGCTGCCCTGGTGCGTCACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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